报告题目：CRISPR/Cas9 and DNA-Encoded Chemistry Technology: Key Genetic and Drug Development Strategies for Human Health

报  告  人：Martin Matthew Matzuk, M.D., Ph.D. 

                  美国国家科学院院士           

           Baylor College of Medicine, USA 

           美国贝勒医学院

     报告时间：2026年4月13日 14:00

                                       报告地点：神经科学研究所401-1500会议室

                                       主  持  人：徐广银 教授

报告人简介：

Dr. Martin M. Matzuk is a renowned physician-scientist and the Chair of the Department of Pathology & Immunology at Baylor College of Medicine (BCM) in Houston, Texas. He also serves as the Founding Director of the Center for Drug Discovery at BCM. Born in New Brunswick, New Jersey, Dr. Matzuk earned his B.A. with Honors in Biology from the University of Chicago and completed his M.D. and Ph.D. at Washington University in St. Louis. His professional career has been deeply rooted at Baylor College of Medicine, where he has been a Professor since 1998 and has held several distinguished chairs, including the Stuart A. Wallace Chair and the Robert L. Moody, Sr. Chair in Pathology & Immunology. Beyond his leadership as Department Chair, he has served as Vice Chair of Research and Interim Chair.

Dr. Matzuk’s research has focused on understanding the molecular mechanisms of reproduction, oncology, and drug discovery. He has made seminal contributions to the field of reproductive biology by using genetic mouse models to identify key genes and signaling pathways—especially the transforming growth factor β (TGFβ) superfamily—that are essential for fertility, ovarian follicle development, and spermatogenesis. His work has direct implications for infertility, ovarian cancer, and the development of novel contraceptives. He has also pioneered the use of DNA-encoded chemical library technology to discover small molecule inhibitors for male contraception and other reproductive tract diseases. Throughout his career, Dr. Matzuk has received numerous prestigious honors, including election to the National Academy of Sciences (2014), the National Academy of Inventors (2016), the inaugural Hill Prize in Medicine (2024), and the Carl G. Hartman Award from the Society for the Study of Reproduction (2022). He holds multiple U.S. patents and has continuously been funded by the National Institutes of Health for over three decades. Dr. Matzuk has also served on various NIH advisory councils and study sections, and as a reviewing editor for journals such as Science. His prolific publication record includes over 280 research articles, and he is a dedicated mentor to numerous graduate students, medical students, and postdoctoral fellows.