程坚博士现任苏州大学神经科学研究所教授、博士生导师。主要研究领域为在脑卒中损伤修复中的胶质细胞机制及药物靶标探索。2009-2011任美国俄勒冈健康科技大学麻醉系助理教授。在美期间作为PI获美国心脏协会卒中研究基金一项。回国后主持国家自然科学基金项目6项、医药生物技术国家重点实验室和新药研究国家重点实验室基金各1项。已在Science Advances等SCI期刊发表论文40余篇；作为第一发明人获药物专利授权3项；担任Stroke、Experimental Neurology等期刊同行评审专家。2017年获教育部科技进步二等奖和江苏省科学技术一等奖。现任中国神经科学学会胶质细胞分会委员、中国卒中学会理事、中国卒中学会转化医学分会委员、江苏省卒中学会常务理事、江苏省卒中学会卒中基础与转化医学专委会主委、江苏省免疫学会神经免疫分会副主委。

代表性论文：

1. Jia Jia*, Zichuang Wang, Minjie Zhang, Caiyun Huang , Yanmei Song, Fuyou Xu, Jingyu Zhang, Jie Li, Meijun He, Yuyao Li, Guizhen Ao, Chengjiao Hong, Yongjun Cao, Y Eugene Chin, Zi-chun Hua, Jian Cheng*. SQR mediates therapeutic effects of H2S by targeting mitochondrial electron transport to induce mitochondrial uncoupling. Science Advance. 2020; 6 (35): eaaz5752.

2. Xiaoling Yan, Fuyou Xu, Jingjing Ji, Peng Song, Yaqin Pei, Meijun He, Zichuang Wang, Shoujiang You, Zichun Hua, Jian Cheng*, Jia J*. Activation of UCP2 by anethole trithione suppresses neuroinflammation after intracerebral hemorrhage. Acta Pharmacologica Sinica. 2021; 0: 1-18

3. Jie Li, Jingyu Zhang, Yusuo Zhang, Zichuang Wang, Yanmei Song, Shanwen Wei, Meijun He, Shoujiang You, Jia Jia*, Jian Cheng*. TRAF2 protects against cerebral ischemia-induced brain injury by suppressing necroptosis. Cell Death Diseases. 2019, 10(5): 328

4. Wei Tang, Rong Cheng, Meng-yue Gao, Min-jin Hu, Lu Zhang, Qiang Wang, Xin-yu Li, Wei Yan, Xiao-ying Wang, Hai-mei Yang, Jian Cheng* and Zi-chun Hua*. A novel annexin dimer targets microglial phagocytosis of astrocytes to protect the brain-blood barrier after cerebral ischemia. Acta Pharmacologica Sinica . 2025 Apr;46(4):852-866

5. Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia*, Jian Cheng*, Yongjun Cao*. Inhibition of SLC11A1-Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke. Advanced Science. 2026 Jan 25:e11482