Name： Liu Yaobo

TeachingTitle：Professor

Phone： 0512-65882526

E-mail： liuyaobo@suda.edu.cn

‌Research Interests：

1）The neural circuit reestablishment and repair in CNS trauma.

2）The molecular and cellular mechanisms underlying regulation of axonal regeneration and neural circuit reestablishment.

3）Principles and advanced technology for the targeted neural modulation in neural circuit reassembly.

Profile of Professor Yaobo Liu

Prof. Yaobo Liu, M.D.&Ph.D., Second-Class Professor, Doctoral Supervisor, Member of the Suzhou Municipal Committee of the Chinese People's Political Consultative Conference (CPPCC), Distinguished Professor at Soochow University, Associate Director of the Institute of Neuroscience, Soochow University, Deputy Chair of the China Democratic League (CDL) Soochow University Committee, and Principal Investigator of the Laboratory for Central Nervous System Circuit Injury and Repair. He is also the Chief Technical Expert for a Major National Research Project and the Technical Lead of the Jiangsu Provincial Engineering Research Center for Neurological Disease Diagnosis and Therapy.

Prof. Yaobo Liu has been the recipient of numerous prestigious talent programs, including the Jiangsu Provincial "Innovation and Entrepreneurship Talent" Program (both individual and team categories), the Jiangsu "333 High-Level Talent Training Project," and the "Six Talent Peaks" Program. He earned his Ph.D. from the Academy of Military Medical Sciences in 2000. From 2003 to 2007, he pursued postdoctoral research at the University of Chicago, USA. He previously held academic appointments as Associate Professor, Professor, and Doctoral Supervisor at the State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, from 2007 to 2012. In 2012, he joined Soochow University, where he currently holds the position of Distinguished Professor and Doctoral Supervisor, and serves as Associate Director of the Institute of Neuroscience.

His research is primarily dedicated to translational neuroscience, with a sustained focus on the mechanistic underpinnings and technological innovations related to neural circuit reconstruction following central nervous system injury. His seminal work has been published in leading peer-reviewed journals, including Nature Neuroscience, Nature Communications, Science Advances, The EMBO Journal, Advanced Science, Cell Research, Cell Discovery, and Advanced Functional Materials. To date, he has served as Principal Investigator (PI) on 24 national and provincial research grants, encompassing Major National Research Projects, Key Projects of the National Natural Science Foundation of China (NSFC), NSFC Regional Innovation and Development Joint Fund Key Projects, six General Programs, the National Major Scientific Research Program (973 Program), Key Special Projects of the National Key R&D Program, and two Jiangsu Provincial Key R&D Program Special Projects. He holds nine authorized patents (both international and national) and has received two Second-Class Provincial/Ministerial Awards for Scientific and Technological Progress. He has also contributed as a co-author to four monographs. His doctoral trainees have been successfully awarded the NSFC Young Student Basic Research Grant (for doctoral candidates) and have been selected for the China Association for Science and Technology (CAST) Young Talent Lifting Program for doctoral students.

Academic Affiliations and Professional Service:

Prof. Yaobo Liu serves as a peer reviewer (both ad hoc and panel) for the NSFC, the National Key R&D Program, and a communication reviewer for Major National Talent Recruitment Projects. He is the Section Editor for Central Nervous System Injury at the international journal Experimental Neurology, and serves on the Editorial Board of the Annals of Clinical and Translational Neurology. His other professional roles include Standing Committee Member of the Neural Regeneration and Repair Committee, Chinese Research Hospital Association; Vice Chair of the Basic Research on Spinal Cord Injury Subcommittee, International Association of Neurorestoratology (China Section); Committee Member of both the Neurodevelopment and Regeneration Division and the Neuroglia Division, Chinese Neuroscience Society; Committee Member of the Stem Cell Physiology Committee, Chinese Physiological Society; Standing Council Member of the Jiangsu Neuroscience Society; and Member of the Academic Committee of Soochow University Medical College.

Public and Social Appointments:

He is a Member of the 15th Suzhou Municipal CPPCC; Deputy Chair of the CDL Soochow University Committee; Deputy Director of the Higher Education Committee, 14th CDL Suzhou Municipal Committee; Member of the Economic and Technological Committee, 14th CDL Suzhou Municipal Committee; and Distinguished Expert (Committee Member) of the Expert Committee of the Jiangsu Provincial Federation of Returned Overseas Chinese.

Selected Peer-reviewed Publications

1、Xiao Zhihang#, Li Tingting#, Zhang Lechi#, Chunya Xia, Zelin Su, Xuyan Ren, Yingjie Fan, Zerui Wu, Yaobo Liu*, Min Su* Magnetically Responsive Piezoelectric Nanocapacitors Enhance Neural Recovery Following Spinal Cord Injury via Targeted Spinal Magnetic Stimulation. Advanced Science. 2026:e14954.

2、Zhe Ji#, Jun Yan#, Chenxi Li, Yuhui Sun, Shoupeng Wang, Jin Tao, Jian Liu*, Yaobo Liu* Precise Rewiring of Corticospinal Axons and Spinal Interneurons via Near- Infrared Optogenetics for Spinal Cord Injury Treatment. Science Advances. 2025. 11(31):eads4938.

3、Kai Zhou#, Wei Wei#, Dan Yang#, Hui Zhang, Wei Yang, Yunpeng Zhang, Yingnan Nie, Mingming Hao, Pengcheng Wang, Hang Ruan, Ting Zhang, Shouyan Wang, Yaobo Liu*. Dual electrical stimulation at spinal-muscular interface reconstructs spinal sensorimotor circuits after spinal cord injury. Nature Communications. 2024. 15(1): 619.

4、Jun Yan#, Yunjing Wan#, Zhe Ji#, Chenxi Li#, Chengcheng Tao, Yunjiao Tang, Yuze Zhang, Yaobo Liu*, Jian Liu*. Motor Neuron-Specific Membrane Depolarization of Transected Peripheral Nerves by Upconversion Nanoparticle-Mediated Optogenetics. Advanced Functional Materials. 2023, 33(50): 2303992.

5、Xin Duan#, Yarong Gao#, Yaobo Liu*. Ryk regulates Wnt5a repulsion of mouse corticospinal tract through modulating planar cell polarity signaling. Cell Discovery. 2017.3:17015.

6、Zhenhui Huang#, Yarong Gao#, Yuhui Sun#, Yue Yin, Chao Zhang, Yasushi Shimoda, Kazutada Watanabe, Yaobo Liu*. NB-3 signaling mediates the cross-talk between post-traumatic spinal axons and scar-forming cells. The EMBO Journal. 2016, 35(16):1745-1765.

7、Lijuan Song#, Yuehui Liu#, Yang Yu#, Xin Duan, Shening Qi, Yaobo Liu*. Shh signaling guides spatial pathfinding of raphespinal tract axons by multidirectional repulsion. Cell Research. 2012, 22(4):697-716.

8、Yaobo Liu, Jun Shi, Chin-Chun Lu, Zheng-Bei Wang, Anna I. Lyuksyutova, Xuejun Song and Yimin Zou*. Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract. Nature Neuroscience. 2005, 8 (9):1151-1159.