Name： Liu Yaobo

TeachingTitleProfessor

Phone： 0512-65882526

E-mail： liuyaobo@suda.edu.cn

‌Research Interests：

1）The neural circuit reestablishment and repair in CNS trauma.

2）The molecular and cellular mechanisms underlying regulation of axonal regeneration and neural circuit reestablishment.

3）Principles and advanced technology for the targeted neural modulation in neural circuit reassembly.

Liu Yaobo, Ph.D., is a Professor and Doctoral Supervisor, Member of the CPPCC of Suzhou, Distinguished Professor of Soochow University, and Deputy Director of the Institute of Neuroscience at Soochow University. He also serves as Vice Chairperson of the Soochow University Committee of the China Democratic League and Director of the Laboratory for Neural Circuit Repair after Central Nervous System Injury. He is Technical Chief Expert for Major National Research Projects and Technical Leader of the Jiangsu Provincial Engineering Research Center for Neurological Disease Diagnosis and Treatment.

Selected for the Jiangsu Province High-Level Innovation and Entrepreneurship Talent Introduction Project, the Jiangsu Provincial Innovation and Entrepreneurship Talent and Innovation and Entrepreneurship Team Projects, the “333 High-Level Talent Training” Project of Jiangsu Province, and the “Six Talent Peaks Project”. He received his Ph.D. from the Academy of Military Medical Sciences in 2000 and conducted postdoctoral research at the University of Chicago, USA. From 2007 to 2012, he served as Associate Professor, Professor, and Doctoral Supervisor at the State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences. Since 2012, he has been appointed as Distinguished Professor, Doctoral Supervisor, and Deputy Director of the Institute of Neuroscience at Soochow University. His research focuses on the mechanisms and technologies underlying neural regeneration and neural circuit reconstruction after central nervous system injury, with a particular emphasis on translational neuroscience. Representative studies from his group have been published in top journals such as Nature Neuroscience, Nature Communications, Science Advances, The EMBO Journal, Advanced Science, Cell Research, Cell Discovery, and Advanced Functional Materials. He has served as Principal Investigator for multiple major national research projects, including National Major Research Project, Key Program of the National Natural Science Foundation of China (NSFC), Key Program of the Joint Fund for Regional Innovation and Development of the NSFC, General Program of the NSFC, Project of the National Basic Research Program of China (973 Program), Project of the Key Special Program of the National Key Research and Development Program, and two Key Special Projects of the Jiangsu Provincial Key Research and Development Program. He has obtained a total of 24 research grants from national, provincial, and ministerial funding agencies. He has been granted nine international and domestic patents, received two Second Prizes of the Provincial and Ministerial Science and Technology Progress Awards, and co-authored three academic monographs. Under his supervision, several doctoral students have been awarded the Basic Research Program for Young Students (PhD Students) of the NSFC and selected for the Young Elite Scientists Sponsorship Program of the China Association for Science and Technology (CAST).

Academic Appointments: Proposal and panel reviewer for the NSFC, the National Key Research and Development Program of China, and national major talent programs; Section Editor for Experimental Neurology (Central Nervous System Injury); Editorial Board Member of Annals of Clinical and Translational Neurology; Standing Committee Member of the Neuroregeneration and Repair Committee of the Chinese Research Hospital Association; Deputy Director of the Basic Research Committee on Spinal Cord Injury, Vice Chair of the Basic Research Committee on Spinal Cord Injury, China Committee of the International Association of Neurorestoratology; Member of the Neurodevelopment and Regeneration Committee and the Glial Biology Committee of the Chinese Neuroscience Society; Member of the Stem Cell Physiology Committee of the Chinese Physiological Society; Standing Committee Member of the Jiangsu Neuroscience Society; and Member of the Academic Committee of Suzhou Medical College, Soochow University.

Social Appointments: Member of the 15th Suzhou Municipal Committee of the CPPCC; Vice Chairperson of the Soochow University Committee of the China Democratic League; Deputy Director of the Higher Education Committee of the 14th Suzhou Municipal Committee of the China Democratic League; Member of the Economic and Science & Technology Committee of the 14th Suzhou Municipal Committee of the China Democratic League; and Specially Appointed Expert (Member) of the Overseas Chinese Expert Committee of the Jiangsu Provincial Federation of Returned Overseas Chinese.

Selected Peer-reviewed Publications

1、Xiao Zhihang#, Li Tingting#, Zhang Lechi#, Chunya Xia, Zelin Su, Xuyan Ren, Yingjie Fan, Zerui Wu, Yaobo Liu*, Min Su* Magnetically Responsive Piezoelectric Nanocapacitors Enhance Neural Recovery Following Spinal Cord Injury via Targeted Spinal Magnetic Stimulation. Advanced Science. 2026:e14954.

2、Zhe Ji#, Jun Yan#, Chenxi Li, Yuhui Sun, Shoupeng Wang, Jin Tao, Jian Liu*, Yaobo Liu* Precise Rewiring of Corticospinal Axons and Spinal Interneurons via Near- Infrared Optogenetics for Spinal Cord Injury Treatment. Science Advances. 2025. 11(31):eads4938.

3、Kai Zhou#, Wei Wei#, Dan Yang#, Hui Zhang, Wei Yang, Yunpeng Zhang, Yingnan Nie, Mingming Hao, Pengcheng Wang, Hang Ruan, Ting Zhang, Shouyan Wang, Yaobo Liu*. Dual electrical stimulation at spinal-muscular interface reconstructs spinal sensorimotor circuits after spinal cord injury. Nature Communications. 2024. 15(1): 619.

4、Jun Yan#, Yunjing Wan#, Zhe Ji#, Chenxi Li#, Chengcheng Tao, Yunjiao Tang, Yuze Zhang, Yaobo Liu*, Jian Liu*. Motor Neuron-Specific Membrane Depolarization of Transected Peripheral Nerves by Upconversion Nanoparticle-Mediated Optogenetics. Advanced Functional Materials. 2023, 33(50): 2303992.

5、Xin Duan#, Yarong Gao#, Yaobo Liu*. Ryk regulates Wnt5a repulsion of mouse corticospinal tract through modulating planar cell polarity signaling. Cell Discovery. 2017.3:17015.

6、Zhenhui Huang#, Yarong Gao#, Yuhui Sun#, Yue Yin, Chao Zhang, Yasushi Shimoda, Kazutada Watanabe, Yaobo Liu*. NB-3 signaling mediates the cross-talk between post-traumatic spinal axons and scar-forming cells. The EMBO Journal. 2016, 35(16):1745-1765.

7、Lijuan Song#, Yuehui Liu#, Yang Yu#, Xin Duan, Shening Qi, Yaobo Liu*. Shh signaling guides spatial pathfinding of raphespinal tract axons by multidirectional repulsion. Cell Research. 2012, 22(4):697-716.

8、Yaobo Liu, Jun Shi, Chin-Chun Lu, Zheng-Bei Wang, Anna I. Lyuksyutova, Xuejun Song and Yimin Zou*. Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract. Nature Neuroscience. 2005, 8 (9):1151-1159.