程坚

  • 姓名: 程坚
  • 职称:教授
  • 联系电话: 0512-65884725
  • E-mail: jiancheng8@hotmail.com

1998获中国药科大学药物化学硕士学位;1998-2001师从扬州大学刘秀梵院士,2001年获预防兽医学博士学位;2001-2003为南京大学医药生物技术国家重点实验室博士后;2003-2009作为博士后在国际著名脑卒中专家Patricia D Hurn领导的研究组从事卒中动物模型及病理机制研究;2009年2月起担任Oregon Health & Science University麻醉系助理教授,在美工作期间作为PI获美国心脏协会(AHA)卒中研究基金一项;2010年4月起兼任第二军医大学PI,2011年2月进入苏州大学神经科学研究所工作。目前已发表研究论文33篇。目前担任国家自然科学基金同行评议专家,美国神经科学会(Society for Neuroscience)、国际脑血流和代谢 (International Society for Cerebral Blood Flow & Metabolism)会员; Stroke, Neuroscience和Restorative Neurology等SCI期刊审稿人。曾于2003年获江苏省科技进步一等奖,2007年获国家发明专利一项。目前主持国家自然科学基金两项、上海市自然科学基金一项。

 

代表性论文:

 

01.  Minjie Zhang, Xiaowei Wu, Yingxiu Xu, Meijun He, Jiaying Yang, Jie Li, Yuyao Li, Guizhen Ao, Jian Cheng#, Jia Jia#. The cystathionine beta-synthase/hydrogen sulfide pathway contributes to microglia-mediated neuroinflammation following cerebral ischemia. Brain, behavior, and immunity (IF: 5.964). 2017 Jul 24. pii: S0889-1591(17)30385-9.  
 
02.  Shuli Zheng, Shanwen Wei, Xiaoyu Wang, Yingxiu Xu, Yunqi Xiao, Hui Liu, Jia Jia#, Jian Cheng#. Sphingosine kinase 1 mediates neuroinflammation following cerebral ischemia. Experimental neurology (IF: 4.657). 2015, 272:160-169.    
 
03.  Xiaomei Zhou, Yongjun Cao, Guizhen Ao, Lifang Hu, Hui Liu, Jian Wu, Xiaoyu Wang, Mengmeng Jin, Shuli Zheng, Xuechu Zhen, Nabil J. Alkayed, Jia Jia, and Jian Cheng#. CaMKKβ-Dependent Activation of AMP-Activated Protein Kinase Is Critical to Suppressive Effects of Hydrogen Sulfide on Neuroinflammation. Antioxidants & Redox Signaling (IF:7.67). 2014, 21(12):1741-1758.
 
04.  Yali Wang, Jia Jia, Guizhen Ao, Lifang Hu, Hui Liu, Yunqi Xiao, Huangping Du, Nabil J. Alkayed, Chun-Feng Liu#, Jian Cheng#. Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia. Journal of Neurochemistry (IF:4.24). 2014, 129(5):827-838.  
 
05.  Yangtai Guan, Lunlin Mao, Jia Jia, Chunsheng Dong, Xiaomei Zhou, Shuli Zheng, Hui Liu, Hongmei Kong, Xuechu Zhen, Jian Cheng#. Post-ischemic administration of a potent PTEN inhibitor reduces spontaneous lung infection following experimental stroke. CNS Neuroscience & Therapeutics (IF: 4.53), 2013, 19(12):990-993.