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程坚

  • 姓名: 程坚
  • 职称:教授
  • 联系电话: 0512-65884725
  • E-mail: chengjian@suda.edu.cn
  • 研究方向: 1.脑缺血保护及修复机制; 2.脑缺血新药设计及开发; 3. 小胶质细胞对脑卒中的作用及调控机制。

  程坚博士,教授,博士生导师,自2003年起一直从事脑卒中损伤及修复机制研究,曾在Oregon Health & Science University麻醉系担任助理教授,在美工作期间作为PI获美国心脏协会(AHA)卒中研究基金一项。近5年,主持国家自然科学基金项目4项、医药生物技术国家重点实验室基金1项;发表SCI论文40余篇;作为第一发明人获得药物专利授权3项;担任Stroke, Neurobiology of Disease, Experimental Neurology, Neuroscience 等国际SCI期刊的同行评审专家;现任中国神经科学学会神经内稳态与内分泌分会专业委员会委员、中国卒中学会转化医学分会委员、江苏省卒中学会常务理事、江苏省卒中学会卒中基础与转化医学专业委员会主任委员、江苏省免疫学会神经免疫分会副主任委员、美国神经科学会和国际脑血流和代谢学会会员;担任国家自然科学基金委同行评审专家。

 

代表性论文:(* Corresponding author)

  1. Jie Li1, Jingyu Zhang1, Yusuo Zhang1, Zichuang Wang, Yanmei Song, Shanwen Wei, Meijun He, Shoujiang You, Jia Jia*, and Jian Cheng*. TRAF2 protects against cerebral ischemia-induced brain injury by suppressing necroptosis. Cell death & disease. 2019 Apr 15, 10(5), 328. (JCR二区)

  2. Minjie Zhang1, Xiaowei Wu1, Yingxiu Xu1, Meijun He, Jiaying Yang, Jie Li, Yuyao Li, Guizhen Ao, Jian Cheng*, and Jia Jia*. The cystathionine beta-synthase/hydrogen sulfide pathway contributes to microglia-mediated neuroinflammation following cerebral ischemia. Brain, behavior, and immunity. 2017 Nov, 66, 332-346. (JCR二区)

  3. Hui Liu1, Yi Wang1, Yunqi Xiao, Zichun Hua, Jian Cheng*, and Jia Jia*. Hydrogen Sulfide Attenuates Tissue Plasminogen Activator-Induced Cerebral Hemorrhage Following Experimental Stroke. Translational stroke research. 2016 Jun, 7, 209-219. (JCR一区)

  4. Shuli Zheng1, Shanwen Wei1, Xiaoyu Wang, Yingxiu Xu, Yunqi Xiao, Hui Liu, Jia Jia*, and Jian Cheng*. Sphingosine kinase 1 mediates neuroinflammation following cerebral ischemia. Experimental neurology. 2015 Oct, 272, 160-169. (JCR二区)

  5. Xiaomei Zhou1, Yongjun Cao1, Guizhen Ao, Lifang Hu, Hui Liu, Jian Wu, Xiaoyu Wang, Mengmeng Jin, Shuli Zheng, Xuechu Zhen, N. J. Alkayed, Jia Jia*, and Jian Cheng*. CaMKKbeta-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation. Antioxidants & redox signaling. 2014 Oct 20, 21, 1741-1758. (JCR一区)